COAGULATION REAGENT COMPLETELY DEVOID OF FACTOR-X - RELATION BETWEEN CLOTTING TIME AND CONCENTRATION OF FACTOR-X

被引:1
作者
VERMEER, C
SOUTE, BAM
HEMKER, HC
机构
[1] Department of Biochemistry, State University of Limburg, Maastricht
关键词
D O I
10.1016/0049-3848(79)90123-3
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A reaction mixture completely devoid of factor X is described. It is shown that no pathways of blood coagulation exist that circumvent this factor. The relation between the clotting time and the inverse of the factor X concentration is shown to be rectilinear. The low KM of the rate-limiting reaction explains why trace amounts of factor X cause short clotting times. © 1979.
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收藏
页码:679 / 685
页数:7
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