INTERACTION BETWEEN BACTERIAL-CELL WALL MODEL AND AGLUCOVANCOMYCIN OR ITS SYNTHETIC ANALOGS

被引：5

作者：

NAKAMURA, K ^{[1
]}

NISHIYAMA, S ^{[1
]}

YAMAMURA, S ^{[1
]}

机构：

[1] KEIO UNIV,FAC SCI & TECHNOL,DEPT CHEM,YOKOHAMA,KANAGAWA 223,JAPAN

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 47期

关键词：

D O I：

10.1016/0040-4039(95)01859-G

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The binding nature of the bacterial cell wall model N-acetyl-D-alanyl-D-alanine with aglucovancomycin (2) as well as synthetic analogs [SAV-1 (3) and SAV-2 (4)] is discussed on the basis of NMR experiments and molecular dynamics calculations. The interaction consists of hydrogen bondings and molecular shape fittings.

引用

页码：8629 / 8632

页数：4

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