PARENTAL IMPRINTING OF AUTOSOMAL MAMMALIAN GENES

被引：200
作者：
EFSTRATIADIS, A
机构：
[1] Department of Genetics and Development, Columbia University, New York, NY 10032
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1994年 / 4卷 / 02期
关键词：
D O I：
10.1016/S0959-437X(05)80054-1
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The molecular mechanisms introducing epigenetic modifications that lead to differential silencing of some autosomal alleles depending on their parental legacy are still largely unknown, but recent results from studies of endogenously imprinted genes and particular transgenes make DNA methylation a strong candidate. At the same time, these results have raised new questions about the details of the imprinting process.
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页码：265 / 280
页数：16
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