DIVERSITY OF THE P2 PROTEIN AMONG NONTYPABLE HAEMOPHILUS-INFLUENZAE ISOLATES

被引：32

作者：

BELL, J

GRASS, S

JEANTEUR, D

MUNSON, RS

机构：

[1] WASHINGTON UNIV,SCH MED,EDWARD MALLINCKRODT DEPT PEDIAT,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,SCH MED,DEPT MOLEC MICROBIOL,ST LOUIS,MO 63110

[3] ST LOUIS CHILDRENS HOSP,DIV INFECT DIS,ST LOUIS,MO 63110

[4] EUROPEAN MOLEC BIOL LAB,W-6900 HEIDELBERG,GERMANY

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 06期

关键词：

D O I：

10.1128/IAI.62.6.2639-2643.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The genes for outer membrane protein P2 of four nontypeable Haemophilus influenzae strains were cloned and sequenced. The derived amino acid sequences were compared with the outer membrane protein P2 sequence from H. influenzae type b MinnA and the sequences of P2 from three additional nontypeable H. influenzae strains. The sequences were 76 to 94% identical. The sequences had regions with considerable variability separated by regions which were highly conserved. The variable regions mapped to putative surface-exposed loops of the protein.

引用

页码：2639 / 2643

页数：5

共 34 条

[1] CLONING, EXPRESSION, AND DNA-SEQUENCE ANALYSIS OF GENES ENCODING NONTYPABLE HAEMOPHILUS-INFLUENZAE HIGH-MOLECULAR-WEIGHT SURFACE-EXPOSED PROTEINS RELATED TO FILAMENTOUS HEMAGGLUTININ OF BORDETELLA-PERTUSSIS [J].