Lowering Glucose to Prevent Adverse Cardiovascular Outcomes in a Critical Care Setting

被引：39
作者：
Ceriello, Antonio [1 ]
Zarich, Stuart W. [2 ]
Testa, Roberto [3 ]
机构：
[1] Univ Warwick, Warwick Med Sch, Ctr Excellence Diabet & Endocrinol, Univ Hosp Coventry & Warwickshire, Coventry CV4 7AL, W Midlands, England
[2] Yale Univ, Sch Med, Div Cardiovasc Med, Bridgeport Hosp, Bridgeport, CT USA
[3] INRCA Ancona, Dept Gerontol Res, Diabetol Unit, Ancona, Italy
来源：
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY | 2009年 / 53卷 / 05期
关键词：
ACUTE MYOCARDIAL-INFARCTION; TIGHT GLYCEMIC CONTROL; RANDOMIZED CONTROLLED-TRIAL; INSULIN-POTASSIUM INFUSION; C-REACTIVE PROTEIN; FREE FATTY-ACIDS; DIABETES-MELLITUS; ILL PATIENTS; VENTRICULAR ARRHYTHMIAS; STRESS HYPERGLYCEMIA;
D O I：
10.1016/j.jacc.2008.09.054
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
High admission blood glucose levels after acute myocardial infarction are common and associated with an increased risk of death in patients with or without diabetes. Hyperglycemia is associated with altered myocardial blood flow and energetics and can lead to a pro-oxidative/proinflammatory state. The use of intensive insulin treatment has shown superior benefits in the treatment of hyperglycemia versus glucose-insulin-potassium infusion, particularly in critical care settings. (J Am Coll Cardiol 2009;53:S9-13) (C) 2009 by the American College of Cardiology Foundation
引用
收藏
页码：S9 / S13
页数：5
相关论文
共 44 条
[1]   Impact of introducing multiple evidence-based clinical practice protocols in a medical intensive care unit: A retrospective cohort study [J].
Afessa B. ;
Gajic O. ;
Keegan M.T. ;
Seferian E.G. ;
Hubmayr R.D. ;
Peters S.G. .
BMC Emergency Medicine, 7 (1)
[2]   HYPERGLYCEMIA AND PROGNOSIS OF ACUTE MYOCARDIAL-INFARCTION IN PATIENTS WITHOUT DIABETES-MELLITUS [J].
BELLODI, G ;
MANICARDI, V ;
MALAVASI, V ;
VENERI, L ;
BERNINI, G ;
BOSSINI, P ;
DISTEFANO, S ;
MAGNANINI, G ;
MURATORI, L ;
ROSSI, G ;
ZUARINI, A .
AMERICAN JOURNAL OF CARDIOLOGY, 1989, 64 (14) :885-888
[3]   Severe hypoglycemia monitoring and risk management procedures in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial [J].
Bonds, Denise E. ;
Kurashige, Ella Mae ;
Bergenstal, Richard ;
Brillon, David ;
Domanski, Michael ;
Felicetta, James V. ;
Fonseca, Vivian A. ;
Hall, Kathleen ;
Hramiak, Irene ;
Miller, Michael E. ;
Osei, Kwame ;
Simons-Morton, Denise G. .
AMERICAN JOURNAL OF CARDIOLOGY, 2007, 99 (12A) :80I-89I
[4]   Stress hyperglycaemia and increased risk of death after myocardial infarction in patients with and without diabetes: a systematic overview [J].
Capes, SE ;
Hunt, D ;
Malmberg, K ;
Gerstein, HC .
LANCET, 2000, 355 (9206) :773-778
[5]   Insulin, glycemic control, and C-reactive protein during myocardial infarction [J].
Ceriello, A .
DIABETES CARE, 2004, 27 (12) :3017-3018
[6]   The hyperglycemia: Intensive insulin infusion in infarction (HI-5) study - A randomized controlled trial of insulin infusion therapy for myocardial infarction [J].
Cheung, NW ;
Wong, VW ;
McLean, M .
DIABETES CARE, 2006, 29 (04) :765-770
[7]   Coronary thrombosis and myocardial infarction, with glycosuria [J].
Cruickshank, N .
BRITISH MEDICAL JOURNAL, 1931, 1931 :618-619
[8]   Insulin as an Anti-Inflammatory and Antiatherogenic Modulator [J].
Dandona, Paresh ;
Chaudhuri, Ajay ;
Ghanim, Husam ;
Mohanty, Priya .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 53 (05) :S14-S20
[9]   Hyperglycemia and acute coronary syndrome - A scientific statement from the American heart association diabetes committee of the council on nutrition, physical activity, and metabolism [J].
Deedwania, Prakash ;
Kosiborod, Mikhail ;
Barrett, Eugene ;
Ceriello, Antonio ;
Isley, William ;
Mazzone, Theodore ;
Raskin, Philip .
CIRCULATION, 2008, 117 (12) :1610-1619
[10]   Glucose-insulin-potassium therapy in patients with ST-segment elevation myocardial infarction [J].
Diaz, Rafael ;
Goyal, Abhinav ;
Mehta, Shamir R. ;
Afzal, Rizwan ;
Xavier, Denis ;
Pais, Prem ;
Chrolavicius, Susan ;
Zhu, Jun ;
Kazmi, Khawar ;
Liu, Lisheng ;
Budaj, Andrzej ;
Zubaid, Mohammad ;
Avezum, Alvaro ;
Ruda, Mikhail ;
Yusuf, Salim .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 298 (20) :2399-2405
12345