REGULATION OF TRANSLATION AND CELL-GROWTH BY EIF-4E

被引：112

作者：

SONENBERG, N ^{[1
]}

机构：

[1] MCGILL UNIV, MCGILL CANC CTR, MONTREAL H3G 1Y6, PQ, CANADA

来源：

BIOCHIMIE | 1994年 / 76卷 / 09期

基金：

英国医学研究理事会;

关键词：

TRANSLATION; EIF-4E; PROTEIN SYNTHESIS; MESSENGER-RNA;

D O I：

10.1016/0300-9084(94)90185-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This review discusses the regulation of a key controlling step in the initiation of protein synthesis, the binding of mRNA to ribosomes. Particular focus is given to the phosphorylation of the cap-binding factor, eIF-4E, and the role of this factor in the regulation of cell growth.

引用

页码：839 / 846

页数：8

共 85 条

[11] REGULATION OF THE INTERFERON-INDUCIBLE EIF-2-ALPHA PROTEIN-KINASE BY SMALL RNAS [J].

CLEMENS, MJ ;

LAING, KG ;

JEFFREY, IW ;

SCHOFIELD, A ;

SHARP, TV ;

ELIA, A ;

MATYS, V ;

JAMES, MC ;

TILLERAY, VJ .

BIOCHIMIE, 1994, 76 (08) :770-778

[12] A NEW YEAST TRANSLATION INITIATION-FACTOR SUPPRESSES A MUTATION IN THE ELF-4A RNA HELICASE [J].

COPPOLECCHIA, R ;

BUSER, P ;

STOTZ, A ;

LINDER, P .

EMBO JOURNAL, 1993, 12 (10) :4005-4011

[13] DIFFERENTIAL EFFICIENCIES OF INVITRO TRANSLATION OF MOUSE C-MYC TRANSCRIPTS DIFFERING IN THE 5' UNTRANSLATED REGION [J].

DARVEAU, A ;

PELLETIER, J ;

SONENBERG, N .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (08) :2315-2319

[14] OVEREXPRESSION OF EUKARYOTIC PROTEIN-SYNTHESIS INITIATION FACTOR-4E IN HELA-CELLS RESULTS IN ABERRANT GROWTH AND MORPHOLOGY [J].

DEBENEDETTI, A ;

RHOADS, RE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (21) :8212-8216

[15]

DONALDSON RW, 1991, J BIOL CHEM, V266, P3162

[16]

DUNCAN R, 1987, J BIOL CHEM, V262, P380

[17] PROTEIN-SYNTHESIS AND PROTEIN-PHOSPHORYLATION DURING HEAT-STRESS, RECOVERY, AND ADAPTATION [J].

DUNCAN, RF ;

HERSHEY, JWB .

JOURNAL OF CELL BIOLOGY, 1989, 109 (04) :1467-1481

[18]

EDERY I, 1983, J BIOL CHEM, V258, P1398

[19]

FAGAN RJ, 1991, J BIOL CHEM, V266, P16518

[20]

FEINGENBLUM D, 1993, J VIROL, V67, P3027

← 1 2 3 4 5 6 7 8 9 →