REGULATION OF TRANSLATION AND CELL-GROWTH BY EIF-4E

被引：112
作者：
SONENBERG, N [1 ]
机构：
[1] MCGILL UNIV, MCGILL CANC CTR, MONTREAL H3G 1Y6, PQ, CANADA
来源：
BIOCHIMIE | 1994年 / 76卷 / 09期
基金：
英国医学研究理事会;
关键词：
TRANSLATION; EIF-4E; PROTEIN SYNTHESIS; MESSENGER-RNA;
D O I：
10.1016/0300-9084(94)90185-6
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review discusses the regulation of a key controlling step in the initiation of protein synthesis, the binding of mRNA to ribosomes. Particular focus is given to the phosphorylation of the cap-binding factor, eIF-4E, and the role of this factor in the regulation of cell growth.
引用
收藏
页码：839 / 846
页数：8
相关论文
共 85 条
[1]  
ABRAMSON RD, 1987, J BIOL CHEM, V262, P3826
[2]   THE 5'-LEADER SEQUENCE OF TOBACCO MOSAIC-VIRUS RNA MEDIATES INITIATION-FACTOR-4E-INDEPENDENT, BUT STILL INITIATION-FACTOR-4A-DEPENDENT TRANSLATION IN YEAST EXTRACTS [J].
ALTMANN, M ;
BLUM, S ;
WILSON, TMA ;
TRACHSEL, H .
GENE, 1990, 91 (01) :127-129
[3]   ORNITHINE DECARBOXYLASE ACTIVITY IS CRITICAL FOR CELL-TRANSFORMATION [J].
AUVINEN, M ;
PAASINEN, A ;
ANDERSSON, LC ;
HOLTTA, E .
NATURE, 1992, 360 (6402) :355-358
[4]   BIOSYNTHESIS OF HUMAN FIBROBLAST GROWTH FACTOR-5 [J].
BATES, B ;
HARDIN, J ;
ZHAN, X ;
DRICKAMER, K ;
GOLDFARB, M .
MOLECULAR AND CELLULAR BIOLOGY, 1991, 11 (04) :1840-1845
[5]   ATP HYDROLYSIS BY INITIATION FACTOR-4A IS REQUIRED FOR TRANSLATION INITIATION IN SACCHAROMYCES-CEREVISIAE [J].
BLUM, S ;
SCHMID, SR ;
PAUSE, A ;
BUSER, P ;
LINDER, P ;
SONENBERG, N ;
TRACHSEL, H .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (16) :7664-7668
[6]   REGULATION OF EUKARYOTIC TRANSLATION INITIATION-FACTOR EXPRESSION DURING T-CELL ACTIVATION [J].
BOAL, TR ;
CHIORINI, JA ;
COHEN, RB ;
MIYAMOTO, S ;
FREDERICKSON, RM ;
SONENBERG, N ;
SAFER, B .
BIOCHIMICA ET BIOPHYSICA ACTA, 1993, 1176 (03) :257-264
[7]  
BONNEAU AM, 1987, J BIOL CHEM, V262, P11134
[8]   CONTINUOUS PROTEIN-SYNTHESIS IS REQUIRED TO MAINTAIN PROBABILITY OF ENTRY INTO S-PHASE [J].
BROOKS, RF .
CELL, 1977, 12 (01) :311-317
[9]  
BU X, 1993, J BIOL CHEM, V268, P4975
[10]   TWO-DIMENSIONAL GEL ANALYSES OF THE 24-KDA CAP BINDING-PROTEIN FROM POLIOVIRUS-INFECTED AND UNINFECTED HELA-CELLS [J].
BUCKLEY, B ;
EHRENFELD, E .
VIROLOGY, 1986, 152 (02) :497-501
123456789