INTERACTION OF PLASMA GELSOLIN WITH TROPOMYOSIN

被引：23

作者：

KOEPF, EK ^{[1
]}

BURTNICK, LD ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,DEPT CHEM,VANCOUVER V6T 1Z1,BC,CANADA

来源：

FEBS LETTERS | 1992年 / 309卷 / 01期

关键词：

GELSOLIN; TROPOMYOSIN;

D O I：

10.1016/0014-5793(92)80738-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Horse plasma gelsolin labelled with benzophenone-4-isothiocyanate can be photochemically cross-linked to rabbit cardiac tropomyosin. The cross-linking proceeds with greater efficiency in calcium-containing buffers. Further evidence for interaction between these proteins is provided by retention of fluorescently labelled gelsolin on tropomyosin-agarose affinity columns and by the ability of tropomyosin to cause an increase in the fluorescence intensity of gelsolin labelled with fluorescein-5-isothiocyanate. Both of these effects require the presence of calcium ions.

引用

页码：56 / 58

页数：3

共 17 条

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