A case of late stage bilateral testicular adrenal rest tumor in 11-beta-hydroxylase deficiency

被引：1

作者：

Ergun, Osman ^{[1
]}

Guzel, Ahmet ^{[1
]}

Tamer, Mehmet Numan ^{[2
]}

Bircan, Sema ^{[3
]}

Armagan, Abdullah ^{[1
]}

机构：

[1] Suleyman Demirel Univ, Tip Fak, Urol Anabilim Dali, Isparta, Turkey

[2] Suleyman Demirel Univ, Tip Fak, Endokrinol & Metabolizma Hastaliklari Bilim Dali, Isparta, Turkey

[3] Suleyman Demirel Univ, Tip Fak, Tibbi Patol Anabilim Dali, Isparta, Turkey

来源：

TURKISH JOURNAL OF UROLOGY | 2011年 / 37卷 / 03期

关键词：

Adrenal hyperplasia; 11-beta-hydroxylase deficiency; testicular adrenal rest tumor;

D O I：

10.5152/tud.2011.049

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 23-year-old man was admitted to our outpatient clinic complaining of infertility and bilateral testicular masses. At physical examination nodular lesions were detected in bilateral testes. The medical history revealed congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency since the age of 2 years. Serum tumor markers were within the normal range. The patient underwent high inguinal testicular exploration; and since differential diagnosis of testicular tumor could not be made with frozen section, high inguinal orchiectomy was performed. The diagnosis of testicular adrenal rest tumor had been confirmed by clinical, morphological, immunohistochemical, laboratory, and endocrinological evaluations, and the patient was referred to endocrinology clinic for future treatment. Clinical control was recommended once a year for testicular masses in left testes.

引用

页码：264 / 268

页数：5

共 16 条

[1] Improved precision of newborn screening for congenital adrenal hyperplasia using weight-adjusted criteria for 17-hydroxyprogesterone levels [J].

Allen, DB ;

Hoffman, GL ;

Fitzpatrick, P ;

Laessig, R ;

Maby, S ;

Slyper, A .

JOURNAL OF PEDIATRICS, 1997, 130 (01) :128-133

[2] Testicular adrenal rest tissue in congenital adrenal hyperplasia: Comparison of MR imaging and sonographic findings [J].

Avila, NA ;

Premkumar, A ;

Merke, DP .

AMERICAN JOURNAL OF ROENTGENOLOGY, 1999, 172 (04) :1003-1006

[3] Testicular adrenal rest tissue in congenital adrenal hyperplasia: Findings at gray-scale and color Doppler US [J].

Avila, NA ;

Premkumar, A ;

Shawker, TH ;

Jones, JV ;

Laue, L ;

Cutler, GB .

RADIOLOGY, 1996, 198 (01) :99-104

[4] UNILATERAL TESTICULAR ENLARGEMENT RESULTING FROM INAPPARENT 21-HYDROXYLASE DEFICIENCY [J].

CHROUSOS, GP ;

LORIAUX, DL ;

SHERINS, RJ ;

CUTLER, GB .

JOURNAL OF UROLOGY, 1981, 126 (01) :127-128

[5] Testicular tumors in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency show functional features of adrenocortical tissue [J].

Claahsen-van der Grinten, Hedi L. ;

Otten, Barto J. ;

Sweep, Fred C. G. J. ;

Span, Paul N. ;

Ross, H. Alec ;

Meuleman, Eric J. H. ;

Hermus, Ad R. M. M. .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2007, 92 (09) :3674-3680

[6]

Claahsen-van der Grinten HL, 2009, INT J PEDIAT ENDOCRI, V2009

[7] EPIDERMOID CYST OF TESTICLE - ULTRASONOGRAPHIC CHARACTERISTICS [J].

COHEN, EL ;

MANDEL, E ;

GOODMAN, JD ;

CARR, L ;

FEIGIN, G ;

DIKMAN, S .

UROLOGY, 1984, 24 (01) :79-81

[8]

CUTFIELD RG, 1983, FERTIL STERIL, V40, P809

[9]

Leotta A., 1994, Pathologica (Genoa), V86, P557

[10]

Levine LS, 2004, NELSON TXB PEDIAT, P1898

← 1 2 →