SUPPRESSION OF ADRENAL METABOLISM OF 4-14C-PROGESTERONE BY TESTOSTERONE-OXIME AND 17ALPHA-METHYLTESTOSTERONE-OXIME IN VITRO

被引：4

作者：

REMBIESA, R

MARCHUT, M

机构：

来源：

BIOCHEMICAL PHARMACOLOGY | 1969年 / 18卷 / 04期

关键词：

D O I：

10.1016/0006-2952(69)90040-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The conversion of 4-14C-progesterone by rat adrenal glands to corticosteroids was studied in vitro following incubation with androst-4-en-17β-ol-3-one oxime (testosterone-oxime) and 17α-methyl-androst-4-en-17β-ol-3-one oxime (methyltestcsterone oxime). The conversion of progesterone to 18-oxygenated steroids: aldosterone and 18-hydroxycorticosterone was decreased to more than one-half of the controls. The amount of 11-deoxycorticosterone was higher than in control experiments. © 1969.

引用

页码：701 / &

共 10 条

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[8] METABOLISM OF 17ALPHA-METHYLANDROSTENEDIOL AND 17ALPHA-METHYLTESTOSTERONE BY RAT ADRENAL GLAND IN VITRO
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