STIMULATION OF RENAL TUBULAR TRANSPORT OF P-AMINOHIPPURATE IN RATS OF DIFFERENT AGES BY TREATMENT WITH ADRENOCORTICAL STEROIDS

被引:0
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作者
BRAUNLICH, H [1 ]
RASSBACH, H [1 ]
VOGELSANG, S [1 ]
机构
[1] FRIEDRICH SCHILLER UNIV,DEPT PHARMACOL & TOXICOL,O-6900 JENA,GERMANY
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关键词
POSTNATAL DEVELOPMENT; P-AMINOHIPPURATE TRANSPORT; PREDNISOLONE; DEXAMETHASONE; TRIAMCINOLONE; DEOXYCORTICOSTERONE; ALDOSTERONE; RAT;
D O I
暂无
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Treatment with prednisolone or dexamethasone is followed by an increase in renal excretion of p-aminohippurate (PAH) and in accumulation of PAH in renal cortical slices, particularly in 5- and 10-day-old rats with immature kidney function. Treatment with triamcinolone is effective both in immature and in 55-day-old rats. There is no stimulation of PAH transport after treatment with mineralocorticoids (desoxycorticosterone, aldosterone).
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页码:1 / 5
页数:5
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