PLACENTAL-TRANSFER OF TETANUS TOXOID ANTIBODIES IN NIGERIAN MOTHERS

被引：17

作者：

HOOD, N ^{[1
]}

CHAN, MCK ^{[1
]}

MAXWELL, SM ^{[1
]}

FAMILUSI, JB ^{[1
]}

HART, CA ^{[1
]}

机构：

[1] UNIV LIVERPOOL,LIVERPOOL SCH TROP MED,DEPT MED MICROBIOL,LIVERPOOL L3 5QA,ENGLAND

来源：

ANNALS OF TROPICAL PAEDIATRICS | 1994年 / 14卷 / 03期

关键词：

D O I：

10.1080/02724936.1994.11747714

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

The aim of this study was to assess the efficacy of the tetanus toxoid immunization programme in Nigeria, specifically the placental transfer of antibody to newborn Nigerian babies. Tetanus toxoid antibody levels were measured in 39 mother-baby pairs in Ibadan, Nigeria and compared with 78 British mother-baby pairs. Geometric means of the ratios of cord/mother (sequestration index SI) were 0.776 for Nigerian pairs and 1.306 for British pairs, indicating a limitation in the placental transfer of tetanus toxoid in the Nigerian population. These findings confirm that there is a block in the placental transfer of anti-tetanus toxoid antibodies in African populations which will affect current immunization programmes and requires further investigation.

引用

页码：179 / 182

页数：4