ANCHOR FOR ONE-STEP RELEASE OF 3'-AMINOOLIGONUCLEOTIDES FROM A SOLID SUPPORT

被引：13

作者：

GRYAZNOV, SM ^{[1
]}

LETSINGER, RL ^{[1
]}

机构：

[1] NORTHWESTERN UNIV,DEPT CHEM,EVANSTON,IL 60208

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 08期

关键词：

OLIGONUCLEOTIDES; AMINES; SOLID SUPPORT TETHER;

D O I：

10.1016/S0040-4039(00)91769-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A linker is described that permits covalently bound aminooligonucleotides to be liberated from a solid support by one step treatment with ammonium hydroxide.

引用

页码：1261 / 1264

页数：4

共 5 条

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NUCLEIC ACIDS RESEARCH, 1991, 19 (07) :1527-1532

[2] SYNTHESIS AND PROPERTIES OF OLIGONUCLEOTIDES CONTAINING AMINODEOXYTHYMIDINE UNITS [J].

GRYAZNOV, SM ;

LETSINGER, RL .

NUCLEIC ACIDS RESEARCH, 1992, 20 (13) :3403-3409

[3] A NEW APPROACH TO SYNTHESIS OF OLIGONUCLEOTIDES WITH 3'PHOSPHORYL GROUPS [J].

GRYAZNOV, SM ;

LETSINGER, RL .

TETRAHEDRON LETTERS, 1992, 33 (29) :4127-4128

[4]

JASTROFF B, 1969, TETRAHEDRON LETT, P2543

[5] NUCLEOTIDE CHEMISTRY .16. PHOSPHORAMIDATE ANALOGS OF OLIGONUCLEOTIDES [J].

LETSINGE.RL ;

MUNGALL, WS .

JOURNAL OF ORGANIC CHEMISTRY, 1970, 35 (11) :3800-&

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