Sleep in Neuromuscular Diseases

被引:16
作者
Fermin, Anna Monica [1 ]
Afzal, Umair [1 ]
Culebras, Antonio [2 ]
机构
[1] SUNY Upstate Med Univ, 750 East Adams St, Syracuse, NY 13210 USA
[2] SUNY Upstate Med Univ, Dept Neurol, 750 East Adams St, Syracuse, NY 13210 USA
关键词
Neuromuscular disease; Neuromuscular junction disorder; Motor neuron disease; Amyotrophic lateral sclerosis; Myasthenia gravis; Spinal cord disorders; Phrenic nerve damage; Myotonic dystrophy;
D O I
10.1016/j.jsmc.2015.10.005
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Sleep disorders in neuromuscular disorders are generally caused by respiratory dysfunction associated with these diseases. Hypoventilation in neuromuscular diseases results from both respiratory muscle weakness and reduced chemoreceptor sensitivity, which is required for ventilatory drive. This condition results in repeated arousals, sleep fragmentation, and nocturnal hypoxemia, manifesting most commonly as excessive daytime somnolence. Polysomnography can identify sleep disordered breathing in patients with neuromuscular disorders and treatment with noninvasive ventilation may improve quality of life.
引用
收藏
页码:53 / +
页数:13
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