BALHIMYCIN, A NEW GLYCOPEPTIDE ANTIBIOTIC WITH AN UNUSUAL HYDRATED 3-AMINO-4-OXOALDOPYRANOSE SUGAR MOIETY

被引：33

作者：

CHATTERJEE, S ^{[1
]}

VIJAYAKUMAR, EKS ^{[1
]}

NADKARNI, SR ^{[1
]}

PATEL, MV ^{[1
]}

BLUMBACH, J ^{[1
]}

GANGULI, BN ^{[1
]}

FEHLHABER, HW ^{[1
]}

KOGLER, H ^{[1
]}

VERTESY, L ^{[1
]}

机构：

[1] HOECHST AG,PHARMACEUT RES,W-6230 FRANKFURT,GERMANY

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1994年 / 59卷 / 12期

关键词：

D O I：

10.1021/jo00091a044

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Balbimycin (1), C66H73Cl2N9O24, is a new glycopeptide antibiotic of the vancomycin class. It was isolated from the fermentation broth of an Amycolatopsis sp. Hoechst India Limited Y-86,21022. Its structure was elucidated on the basis of spectroscopic and chemical degradation studies. The aglycon is identical to that of vancomycin. The molecule contains two sugars, D-glucose and dehydrovancosamine. The latter unit remains as a hydrate in solution.

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页码：3480 / 3484

页数：5

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