EFFECT OF POTASSIUM-CHLORIDE ON GASTRIC-ACID SECRETION AND GASTRIN-RELEASE IN HUMANS

被引：0

作者：

FELDMAN, M

GOLDSCHMIEDT, M

机构：

来源：

ALIMENTARY PHARMACOLOGY & THERAPEUTICS | 1992年 / 6卷 / 04期

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暂无

中图分类号：

R57 [消化系及腹部疾病];

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摘要：

The effect of potassium chloride on gastric acid secretion and gastrin release was studied in 6 healthy human beings. On 3 separate days and in random order, subjects received an intragastric infusion of 0.5 L of a glucose-saline solution to which had been added 40 mmol KCl, 40 mmol NaCl, or no additional salts. All test solutions stimulated acid secretion and gastrin release to a similar degree. While potassium ions play a critical role in acid secretion by parietal cells (via the H+, K+-ATPase), KCl administered into the gastric lumen at a concentration of 80 mmol/L has no effect on acid secretion in man.

引用

页码：407 / 414

页数：8