EFFECT OF OSMOLAR CHANGES ON PLASMA ARGININE VASOPRESSIN (PAVP) IN DIALYSIS PATIENTS

被引:0
|
作者
ROSANSKY, SJ
RHINEHART, R
SHADE, R
机构
[1] UNIV S CAROLINA, SCH MED, DEPT MED, COLUMBIA, SC 29208 USA
[2] SW FDN BIOMED RES, SAN ANTONIO, TX 78284 USA
关键词
VASOPRESSIN; OSMOLALITY; HEMODIALYSIS; VOLUME;
D O I
暂无
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The effect of changes in plasma osmolality and changes in plasma arginine vasopressin (PAVP) were analyzed in 10 stable chronic hemodialysis patients utilizing four protocols. During regular hemodialysis opposing influences on PAVP (decrease in blood pressure and intravascular volume and increase in serum calcium) resulted in no significant change in PAVP (by analysis of variance). In the second protocol low dialysate calcium (2.5 meq/l) isovolemic hemodialysis was used. PAVP and serum osmolality levels declined from 2.0 +/- 0.4 to 1.4 +/- 0.2-mu-U/ml (p < 0.05), and 285 +/- 2.5 mOsm/l to 275 +/- 3.2 mOsm/l respectively. Removal of PAVP by hemodialysis did not occur as evidenced by no difference in arterial-venous PAVP levels and no "rebound" of PAVP for three hours after completion of dialysis (second protocol). Isovolemic low calcium high dialysate sodium (145 meq/l) hemodialysis was utilized in the third protocol. Serum osmolality and PAVP did not change. Addition of a very high dialysate sodium (155 meq/l) to isovolemic low calcium hemodialysis resulted in an increase in plasma sodium, osmolality and AVP (139.7 +/- 0.62 to 144 +/- 0.67 meq/l, 294 +/- 2.79 to 304.3 +/- 2.4 mOsm/l and 1.8 +/- 0.3 to 2.7 +/- 0.5-mu-U/ml (p < 0.05 for each) respectively. In conclusion, PAVP responds to changes in plasma osmolality in chronic hemodialysis patients.
引用
收藏
页码:158 / 164
页数:7
相关论文
共 50 条
  • [1] Isosorbide-Induced Decompression Effect on the Scala Media: Participation of Plasma Osmolality and Plasma Arginine Vasopressin
    Takeda, Taizo
    Takeda, Setsuko
    Uehara, Natsumi
    Yanagisawa, Shungaku
    Furukawa, Tatsuya
    Nibu, Ken-ichi
    Kakigi, Akinobu
    OTOLOGY & NEUROTOLOGY, 2017, 38 (04) : 599 - 605
  • [2] ARGININE VASOPRESSIN RESPONSE TO HYPERTONICITY IN HYPERTENSION STUDIED BY ARGININE VASOPRESSIN ASSAY IN UNEXTRACTED PLASMA
    HENNEBERRY, HP
    SLATER, JDH
    EISEN, V
    FUHR, S
    JOURNAL OF HYPERTENSION, 1992, 10 (03) : 221 - 228
  • [3] Fluid deprivation in enuresis - Effect on urine output and plasma arginine vasopressin
    Hunsballe, J
    Rittig, S
    Pedersen, EB
    Djurhuus, JC
    SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, 1999, 33 : 50 - 51
  • [4] Changes in plasma arginine vasopressin concentrations in cyclists participating in a 109-km cycle race
    Hew-Butler, T.
    Dugas, J. P.
    Noakes, T. D.
    Verbalis, J. G.
    BRITISH JOURNAL OF SPORTS MEDICINE, 2010, 44 (08) : 594 - 597
  • [5] The Origin of the Hydroosmotic Effect of Arginine Vasopressin: A Hypothesis
    Yu. V. Natochin
    E. I. Shakhmatova
    Doklady Biological Sciences, 2003, 389 (1-6) : 96 - 98
  • [6] THE ROLE OF POSTURE ON THE CHANGES IN PLASMA ATRIAL-NATRIURETIC-FACTOR AND ARGININE VASOPRESSIN LEVELS DURING IMMERSION
    WOLF, JP
    NGUYEN, NU
    BAULAY, A
    DUMOULIN, G
    BERTHELAY, S
    EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY AND OCCUPATIONAL PHYSIOLOGY, 1990, 61 (3-4): : 284 - 288
  • [7] Ropinirole does not affect plasma arginine vasopressin levels in patients with advanced Parkinson's disease
    Arai, Motomi
    NEUROENDOCRINOLOGY LETTERS, 2012, 33 (07) : 680 - 683
  • [8] Increased plasma arginine vasopressin levels in dopamine agonist-treated Parkinson's disease patients
    Arai, Motomi
    NEUROENDOCRINOLOGY LETTERS, 2011, 32 (01) : 39 - 43
  • [9] Levels of arginine and its products in dialysis patients
    Ugurcu, V.
    Vatansev, H.
    Unlu, A.
    Sivrikaya, A.
    Akyurek, F.
    Ozturk, B.
    Kiyici, A.
    Erdem, S. S.
    EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, 2014, 18 (16) : 2357 - 2364
  • [10] Plasma arginine vasopressin response to hypertonic saline infusion in Alzheimer disease
    Peskind, ER
    Pascualy, M
    Edland, SD
    Wingerson, D
    Dobie, DJ
    Raskind, MA
    ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1995, 9 (04): : 238 - 242