COMBINATORIAL CHEMISTRY

被引:103
作者
LOWE, G
机构
[1] Dyson Perrins Laboratory, Oxford University, South Parks Road, Oxford OX1 3QY, United Kingdom
关键词
D O I
10.1039/cs9952400309
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Combinatorial chemistry is a novel way of rapidly generating a large number of related compounds. Screening of such a collection or library for biological activity may be performed in solution or on a solid support. Combinatorial peptide libraries have been most intensively investigated in the search for lead compounds, but the method is so powerful that it seems certain that it will be used increasingly to generate libraries of other types of molecule.
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页码:309 / &
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