COMPLEXATION OF GLUCOSE BY ALPHA-CYCLODEXTRINS AND BETA-CYCLODEXTRINS

被引：19
|
作者：
HIRSCH, W
MULLER, T
PIZER, R
RICATTO, PJ
机构：
[1] Department of Chemistry, Brooklyn College, City University of New York, Brooklyn
来源：
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE | 1995年 / 73卷 / 01期
关键词：
ALPHA-; BETA-CYCLODEXTRIN; GLUCOSE; BINDING CONSTANTS;
D O I：
10.1139/v95-003
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The concentration of glucose in aqueous solutions was monitored, using a blood glucose meter, as small weighed cyclodextrin portions were added, Equilibrium constants for the formation of inclusion complexes were calculated. A binding constant determined by this method has been verified by a technique involving competition of the guest with methyl orange indicator dye. Delta H-0 values for the reactions were estimated using calorimetry. These values along with Delta G(0) provided estimates of the standard entropies. The values calculated compare favorably with those from a previously determined empirical equation. The possibility of hydrogen bond formation is suggested by the large negative enthalpies as well as by molecular mechanics calculations.
引用
收藏
页码：12 / 15
页数：4
相关论文
共 50 条
12345