8-Benzyloxy-2-methyl-3-(2-methyl-phenyl)quinazolin-4(3H)-one

被引：0

作者：

El-Azab, Adel S. ^{[1
,2
]}

Abdel-Aziz, Alaa A. -M. ^{[1
,3
]}

Ng, Seik Weng ^{[4
,5
]}

Tiekink, Edward R. T. ^{[4
]}

机构：

[1] King Saud Univ, Coll Pharm, Dept Pharmaceut Chem, Riyadh 11451, Saudi Arabia

[2] Al Azhar Univ, Fac Pharm, Dept Organ Chem, Cairo 11884, Egypt

[3] Univ Mansoura, Fac Pharm, Dept Med Chem, Mansoura 35516, Egypt

[4] Univ Malaya, Dept Chem, Kuala Lumpur 50603, Malaysia

[5] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah, Saudi Arabia

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2012年 / 68卷

关键词：

data-to-parameter ratio = 15.4; disorder in main residue; mean σ(C-C) = 0.002 Å; R factor = 0.048; single-crystal X-ray study; T = 100 K; wR factor = 0.121;

D O I：

10.1107/S1600536812007362

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

In the title methaqua-lone analogue, C 23H 20N 2O 2, the planes of the terminal aromatic rings [dihedral angle between them = 64.52 (7)°] approximately face the fused-ring methyl group and both are twisted with respect to the pyrimidine plane (r.m.s. deviation = 0.028 Å), forming dihedral angles of 86.9 (3) (with the 2-tolyl ring) and 65.57 (7)°. The 2-tolyl residue is disordered over two almost coplanar but opposite orientations with the major component having a site-occupancy factor of 0.893 (3). The three-dimensional crystal packing is consolidated by C - H⋯O, C - H⋯π and π-π [2-tol-yl-2-tolyl centroid-centroid distance = 3.8099 (6) Å] interactions.

引用

页码：O864 / U3151

页数：11

共 9 条

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