Synthesis and antibacterial evaluation of some novel chalcones and their derivatives

被引：0
|
作者：
Solankee, Anjani [1 ]
Patel, Ghanshyam [1 ]
机构：
[1] BKM Sci Coll, Dept Chem, Valsad 396001, India
来源：
ORIENTAL JOURNAL OF CHEMISTRY | 2010年 / 26卷 / 03期
关键词：
Chalcones; acetylprazolines; aminopyrimidines; cyanopyridines; spectral data;
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Chalcones (6a-e) have been prepared by the condensation of ketone (5) and different aromatic aldehydes. These chalcones (6a-e) on treatment with hydrazine hydrate, guanidine hydrochloride and malononitrile give acetylpyrazolines (7a-e) aminpyrimidines (8a-e) and cyanopyridines (9a-e) respectively. All the newly synthesized compounds have been characterized on the basis of IR, 1H NMR Spectral data as well as physical data. The compounds were tested for their antibacterial activity by uing agar diffusion method.
引用
收藏
页码：1061 / 1065
页数：5
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