INDUCTION OF INTERFERON SYNTHESIS IN RAINBOW-TROUT LEUKOCYTES BY VARIOUS HOMEOTHERM VIRUSES

被引:8
作者
SNEGAROFF, J
机构
[1] Laboratoire de Virologie et Immunologie Moléculaires, I.N.R.A.
关键词
TROUT; KIDNEY LEUKOCYTES; INTERFERON; INDUCTION IN-VITRO;
D O I
10.1006/fsim.1993.1019
中图分类号
S9 [水产、渔业];
学科分类号
0908 ;
摘要
Interferon synthesis by leucocytes from rainbow trout kidney was induced in vitro by contact with various viruses. The best inducer found was Newcastle disease virus (NDV), followed by two coronaviruses (porcine TGEV and a bovine coronavirus). Interferon was also produced by leucocytes stimulated with viral haemorrhagic septicaemia virus-infected and glutaraldehyde-fixed cells, but the titre was much lower. The secretion of interferon stimulated by NDV was detectable 24 h after induction. The interferon so obtained protected young trout against VHSV when injected at the time of infection. © 1993 Academic Press. All rights reserved.
引用
收藏
页码:191 / 198
页数:8
相关论文
共 19 条
[1]  
Charley B., Laude H., Induction of alpha interferon by transmissible gastroenteritis coronavirus: Role of transmembrane glycoprotein El, Journal of Virology, 62, 1, pp. 8-11, (1988)
[2]  
De Kinkelin P., Dorson M., Interferon production in rainbow trout (Salmo gairdneri) experimentally infected with Egtved virus, Journal of General Virology, 19, pp. 125-127, (1973)
[3]  
De Kinkelin P., Dorson M., Hattenberger-Baudouy A.M., Interferon synthesis in trout and carp after viral infection, Developmental and Comparative Immunology, pp. 167-174, (1982)
[4]  
De Kinkelin P., Le Berre M., Necrose Hematopoietique Des Salmonides: Production d’interferon Circulant Induite Apres l’infection Experimentale De La Truite Arc-En-Ciel (Salmo Gairdneri), 279, pp. 445-448, (1974)
[5]  
De Sena J., Rio G.J., Partial purification and characterization of RTG2 fish cell interferon, Infection and Immunity, 11, 4, pp. 815-822, (1975)
[6]  
Dorson M., De Kinkelin P., Mortalite et production d’interferon circulant chez la truite arc-en-ciel apres infection experimentale par le virus d’Egtved: Influence de la temperature, Annales Des Recherches Veterinaires, 5, 3, pp. 365-372, (1974)
[7]  
Dorson M., De Kinkelin P., Torhy C., Interferon synthesis in rainbow trout fry following infection by infectious pancreatic necrosis virus, Fish and Shellfish Immunology, 2, pp. 311-313, (1992)
[8]  
Eaton W.D., Antiviral activity in four species of salmonids following exposure to poly(I)-poly(C), Diseases of Aquatic Organisms, 9, pp. 193-198, (1990)
[9]  
Gaillard C., Chilmonczyk S., De Kinkelin P., Interferon synthesis induced by viral hemorrhagic septicaemia virus (VHSV) in rainbow trout leucocytes in vitro, Proceedings of the Xhiih Fish Health Section/American Fisheries Society Meeting, (1989)
[10]  
Graham S., Secombes C.J., Do fish lymphocytes secrete interferon-gamma?, Journal of Fish Biology, 36, pp. 563-573, (1990)