REPEATED DNA IN PNEUMOCYSTIS-CARINII

被引：46

作者：

STRINGER, SL ^{[1
]}

HONG, ST ^{[1
]}

GIUNTOLI, D ^{[1
]}

STRINGER, JR ^{[1
]}

机构：

[1] UNIV CINCINNATI, COLL MED, DEPT MOLEC GENET BIOCHEM & MICROBIOL, CINCINNATI, OH 45267 USA

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 1991年 / 29卷 / 06期

关键词：

D O I：

10.1128/JCM.29.6.1194-1201.1991

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A 16-kb DNA fragment designated Rp3-1 and cloned from the genome of rat-derived Pneumocystis carinii was found to contain sequences that were repeated approximately 70 times per genome. The repeated sequences in Rp3-1 spanned at least 10.4 kb. Sequences in Rp3-1 were present on each of the 16 P. carinii chromosomes resolved by field inversion gel electrophoresis. Most of the P. carinii genomic sequences homologous to those in the Rp3-1 clone appeared to be as long as those in the Rp3-1 clone but were highly polymorphic with respect to restriction enzyme cleavage sites. The Rp3-1 DNA fragment appears to be a member of a family of large, degenerate, dispersed repeats.

引用

页码：1194 / 1201

页数：8

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