RESPONSES OF SNAIL MUSCLE-FIBERS TO ACETYLCHOLINE AND SEROTONIN

被引：9

作者：

PETERS, M

机构：

[1] Institut für Zoologie, RWTH-Aachen, 51 Aachen, BRD

来源：

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY | 1979年 / 62卷 / 02期

关键词：

D O I：

10.1016/0306-4492(79)90007-8

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

1. The effects of acetylcholine, serotonin and some blocking agents on membrane potential of muscle fibres in the pharynx levator muscle of Helix pomatia were assayed. 2. Bath-application of ACh results in depolarization (threshold ca. 10-7M). Above ca. 5 × 10-5M depolarization is followed by a long-lasting hyperpolarization. 3. d-Tubocurarine blocks the response to ACh and lowers the amplitude of nerve-evoked EPSPs. Atropine blocks ACh-hyperpolarization. 4. Serotonin (above 10-7) causes hyperpolarization of the resting membrane, but does not repolarize membrane from ACh depolarization. © 1979.

引用

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页码：181 / 185

页数：5

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