STUDIES ON POLYAMINE BIOSYNTHESIS IN EUGLENA-GRACILIS

被引：22

作者：

ALEKSIJEVIC, A

GROVE, J

SCHUBER, F

机构：

[1] UNIV LOUIS PASTEUR,INST BOT,F-67000 STRASBOURG,FRANCE

[2] MERRELL INT,CTR RECH,F-67084 STRASBOURG,FRANCE

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1979年 / 565卷 / 01期

关键词：

(Euglena gracilis); Norspermidine; Norspermine; Ornithine decarboxylase; Polyamine biosynthesis; S-Adenosyl methionine decarboxylase;

D O I：

10.1016/0005-2787(79)90096-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Euglene gracilis (strain Z) was found to contain five polyamines which could be separated by high-pressure cation-exchange chromatography. 1,3-Diaminopropane, putrescine, norspermidine (N-(3-aminopropyl)-1,3-diaminopropane), spermidine and norspermine (N,N′-bis(aminopropyl)-1,3-diaminopropane) were identified. Biosynthesis of putrescine in E. gracilis proceeds through decarboxylation of l-ornithine, no arginine decarboxylase (EC 4.1.1.19) activity could be detected. The properties of the enzymes ornithine decarboxylase (EC 4.1.1.17) and S-adenosylmethionine decarboxylase (EC 4.1.1.50) in this alga were found to be similar to those of the enzymes isolated from animal tissues or yeast cells. A biosynthetic scheme is proposed which relates the different polyamines occurring in E. gracilis. © 1979.

引用

页码：199 / 207

页数：9

共 33 条

[1] POLYAMINE LEVELS IN NORMAL HUMAN-SERUM - COMPARISON OF ANALYTICAL METHODS [J].