Interpersonal theories of depression postulate that depressed individuals' experience of social isolation is attributable, in part, to their tendency to behave in ways that elicit rejection from others. Depression contagion has been implicated as a factor that may account for the rejection of depressed individuals. In the current study, we revisit this hypothesis by using a controlled, but realistically motivated, setting: speed dating. Approximately 2 weeks before the speed-dating event, participants' depression levels were assessed. During the event, participants had 4-min "dates" with opposite-sex partners. After each date, they responded to items that measured their affect and romantic attraction. At the end of the evening, participants indicated which partners they wanted to see again. Our results did not support depression contagion: After 4 min of interaction with partners with high levels of depressive symptoms, participants did not experience increased negative affect; instead, they experienced reduced positive affect, which led to the rejection of these partners.