SNAPS AND NSF - GENERAL MEMBERS OF THE FUSION APPARATUS

被引：87
|
作者：
WHITEHEART, SW [1 ]
KUBALEK, EW [1 ]
机构：
[1] STANFORD UNIV,HOWARD HUGHES MED INST,DEPT BIOCHEM,STANFORD,CA 94305
来源：
TRENDS IN CELL BIOLOGY | 1995年 / 5卷 / 02期
关键词：
D O I：
10.1016/S0962-8924(00)88948-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The proteins NSF and SNAPs are known to participate in several intracellular fusion events, but their exact functions in the fusion process are unclear. Molecular studies have now shown that the ability of NSF to hydrolyse ATP is essential form membrane fusion and that this activity is regulated by SNAPs. This article reviews recent work on NSF and SNAPs, and speculates about how they interact with each other and SNAREs to promote membrane fusion.
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收藏
页码：64 / 68
页数：5
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