ESTIMATING THE PROPORTION OF IMMUNES IN CENSORED SAMPLES - A SIMULATION STUDY

被引：16

作者：

GHITANY, ME ^{[1
]}

MALLER, R ^{[1
]}

ZHOU, S ^{[1
]}

机构：

[1] UNIV WESTERN AUSTRALIA,DEPT MATH,NEDLANDS,WA 6009,AUSTRALIA

来源：

STATISTICS IN MEDICINE | 1995年 / 14卷 / 01期

关键词：

D O I：

10.1002/sim.4780140106

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

We review currently known results concerning the estimation of an 'immune' or 'cured' proportion, and testing for the presence of immunes, in censored survival data, suggesting that a firm theoretical foundation now exists for analysis. Two types of estimators, parametric and non-parametric, are discussed and compared with respect to their theoretical properties, and, by simulation, with respect to their small sample behaviour. Both estimators have advantages and drawbacks, but together provide powerful tools for the perceptive analysis of survival data with, or even without, immune individuals.

引用

页码：39 / 49

页数：11

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