DIAGNOSTIC ACCURACY OF ENDOCERVICOSCOPY AS PREOPERATIVE TOOL TO IMPROVE THE EXCISIONAL TREATMENT OF CERVICAL PRENEOPLASTIC LESIONS

被引:6
作者
De Franciscis, Pasquale [1 ,2 ]
La Manna, Viviana [1 ,2 ]
Schiattarella, Antonio [1 ,2 ]
Ambrosio, Domenico [1 ,2 ]
Labriola, Domenico [1 ,2 ]
Procaccianti, Roberto [1 ,2 ]
Ammaturo, Franco P. [1 ,2 ]
Morlando, Maddalena [1 ,2 ]
Torella, Marco [1 ,2 ]
机构
[1] Univ Campania Luigi Vanvitelli, Dept Woman & Child, Obstet & Ginecol Ctr, Largo Madonna Grazie 1, I-80138 Naples, Italy
[2] Univ Campania Luigi Vanvitelli, Dept Gen & Specialist Ctr, Obstet & Ginecol Ctr, Naples, Italy
来源
MINERVA GINECOLOGICA | 2018年 / 70卷 / 04期
关键词
Colposcopy; Cervical intraepithelial neoplasia; Therapeutics;
D O I
10.23736/S0026-4784.18.04196-5
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
BACKGROUND: The aim of this study was to evaluate the diagnostic accuracy of endocervicoscopy as a preoperative examination to improve the outcome of the excisions' treatment (LEEP) of high-grade cervical preneoplastic lesions. METHODS: Patients with histologic diagnosis of CIN II-CIN III undergoing LEEP divided in two groups: in group A (85 women) a preoperative endocervicoscopy was performed, in group B (85 women) no additional examination was performed before LEER. The size of the surgical specimen (H, D, W) and the margins of the lesion were evaluated. RESULTS: Seventy-four women in group A and 80 in group B completed the follow-up. group A showed significant correlation between colposcopic examination and endocervicoscopic examination (P=0.001, k=0.30) and between endocervicoscopic and defimtive histological examination (P<0.05, k=0.16). The depth of the operative sample was significantly lower (P<0.0001) in group A (0.91 +/- 10.4) than in group B (1.58 +/- 0.2), group A showed fewer patients B with positive endocervical margins than group B (3 vs. 17, P<002). Colposcopic, cytological and virological follow-up did not show significant differences between the two groups. CONCLUSIONS: Endocervicoscopy as preoperative tool for excisional treatment of cervical lesions showed high diagnostic effectiveness and allows to perform a conservative surgery.
引用
收藏
页码:364 / 370
页数:7
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