ON THE RAT MODEL OF HUMAN OSTEOPENIAS AND OSTEOPOROSIS

被引：376
作者：
FROST, HM
JEE, WSS
机构：
[1] UNIV UTAH, SCH MED, DIV RADIOBIOL, BLDG 586, SALT LAKE CITY, UT 84112 USA
[2] SO COLORADO CLIN, DEPT ORTHOPAED SURG, PUEBLO, CO USA
来源：
BONE AND MINERAL | 1992年 / 18卷 / 03期
关键词：
RAT; OSTEOPOROSIS; OSTEOPENIA; BONE MODELING; BONE REMODELING; MECHANICAL AND NONMECHANICAL AGENTS;
D O I：
10.1016/0169-6009(92)90809-R
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The idea that rats cannot model human osteopenias errs. The same mechanisms control gains in bone mass (longitudinal bone growth and modeling drifts) and losses (BMU-based remodeling), in young and aged rats and humans. Furthermore, they respond similarly in rats and man to mechanical influences, hormones, drugs and other agents.
引用
收藏
页码：227 / 236
页数：10
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