Periodontal Disease-Induced Atherosclerosis and Oxidative Stress

被引：29

作者：

Kurita-Ochiai, Tomoko ^{[1
]}

Jia, Ru ^{[2
]}

Cai, Yu ^{[3
]}

Yamaguchi, Yohei ^{[4
]}

Yamamoto, Masafumi ^{[1
]}

机构：

[1] Nihon Univ, Sch Dent Matsudo, Dept Microbiol & Immunol, Chiba 2718587, Japan

[2] Tongji Univ, Stomatol Hosp, Shanghai 200072, Peoples R China

[3] Peking Univ, Sch & Hosp Stomatol, Dept Periodontol, Beijing 100081, Peoples R China

[4] Tokyo Womens Med Univ, Sch Med, Dept Oral & Maxillofacial Surg, Tokyo 1628666, Japan

来源：

ANTIOXIDANTS | 2015年 / 4卷 / 03期

基金：

日本学术振兴会;

关键词：

inflammation; oxidative stress; systemic chronic disease; atherosclerosis; periodontal disease;

D O I：

10.3390/antiox4030577

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Periodontal disease is a highly prevalent disorder affecting up to 80% of the global population. Recent epidemiological studies have shown an association between periodontal disease and cardiovascular disease, as oxidative stress plays an important role in chronic inflammatory diseases such as periodontal disease and cardiovascular disease. In this review, we focus on the mechanisms by which periodontopathic bacteria cause chronic inflammation through the enhancement of oxidative stress and accelerate cardiovascular disease. Furthermore, we comment on the antioxidative activity of catechin in atherosclerosis accelerated by periodontitis.

引用

页码：577 / 590

页数：14

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