Microcephaly in Piaui, Brazil: descriptive study during the Zika virus epidemic, 2015-2016

被引：15

作者：

Ribeiro, Igor Goncalves ^{[1
]}

de Andrade, Marcia Regina ^{[1
]}

Silva, Janaina de Moraes ^{[2
]}

Silva, Zenira Martins ^{[2
]}

de Oliveira Costa, Maria Amelia ^{[2
]}

da Cunha e Silva Vieira, Marcelo Adriano ^{[3
]}

de Araujo Batista, Francisca Miriane ^{[2
]}

Guimaraes, Herlon ^{[2
]}

Wada, Marcelo Yoshito ^{[1
]}

Saad, Eduardo ^{[1
]}

机构：

[1] Secretaria Vigilancia Saude, Minist Saude, Brasilia, DF, Brazil

[2] Secretaria Estado Saude Piaui, Superintendencia Atencao Integral Saude, Teresina, PL, Brazil

[3] Secretaria Estado Saude Piaui, Inst Doencas Trop Natan Portella, Teresina, PL, Brazil

来源：

EPIDEMIOLOGIA E SERVICOS DE SAUDE | 2018年 / 27卷 / 01期

关键词：

Microcephaly; Zika Virus Infection; Epidemiology; Descriptive;

D O I：

10.5123/S1679-49742018000100002

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Objective: to describe the occurrence and characteristics of microcephaly cases in Piaui, Brazil, during an epidemic of Zika virus infection in 2015-2016. Methods: descriptive study using data of live births from January/2015 to January/2016, obtained from the Information System on Live Births (Sinasc), the Public Health Events Registry (RESP) and the active search for medical records; mothers and live births were tested for dengue, chikungunya, and Zika, besides syphilis, toxoplasmosis, rubella, cytomegalovirus, and herpes (STORCH). Results: of the 75 microcephaly cases, 34 were related to congenital infectious process; microcephaly prevalence was of 13.6/10 thousand live births; imaging exams confirmed that 34 live births presented calcifications, 23 had cerebral atrophies, 14 had lissencephaly, 12 had ventriculomegaly and 6 had dysgenesis; none tested positive for STORCH, dengue or chikungunya; 1 was IgM positive for Zika. Conclusion: there was an outbreak of microcephaly in Piaui, possibly related to infection during pregnancy Zika virus.

引用

页数：10

共 29 条

[1]

Aragao MFV, BMJ

[2]

Brasil. Ministerio da Saude, 2016, B EPIDEMIOL, V47, P1

[3] ECLAMC: The Latin-American Collaborative Study of Congenital Malformations [J].

Castilla, EE ;

Orioli, IM .

COMMUNITY GENETICS, 2004, 7 (2-3) :76-94

[4] A systematic review and meta-analysis to revise the Fenton growth chart for preterm infants [J].

Fenton, Tanis R. ;

Kim, Jae H. .

BMC PEDIATRICS, 2013, 13

[5]

Ferreira H, 2000, ACTA PEDIAT PORT, V31, P11

[6]

Figueiredo Luiz Tadeu Moraes, 1994, Revista do Instituto de Medicina Tropical de Sao Paulo, V36, P417, DOI 10.1590/S0036-46651994000500005

[7]

Herrero MM, 2008, PROTOCOLOS DIAGNOSTI, V1, P185

[8]

Leal Maria do Carmo, 2015, Rev. Bras. Saude Mater. Infant., V15, P91, DOI 10.1590/S1519-38292015000100008

[9] Quality of birth defect reporting in the Brazilian Information System on Live Births (SINASC): a comparative study of 2004 and 2007 [J].

Luquetti, Daniela Varela ;

Koifman, Rosalina Jorge .

CADERNOS DE SAUDE PUBLICA, 2010, 26 (09) :1756-1765

[10]

Marinho F, 2016, EPIDEMIOL SERV SAUDE, V25, P701, DOI [10.5123/s1679-49742016000400004, 10.5123/S1679-49742016000400004]

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