PHOSPHORYLATION, ALLOSTERIC EFFECTORS AND INTER-DOMAIN CONTACTS IN CAD - THEIR ROLE IN REGULATION OF EARLY STEPS OF PYRIMIDINE BIOSYNTHESIS

被引：12
作者：
CARREY, EA
机构：
来源：
BIOCHEMICAL SOCIETY TRANSACTIONS | 1993年 / 21卷 / 01期
基金：
英国惠康基金;
关键词：
D O I：
10.1042/bst0210191
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：191 / 195
页数：5
相关论文
共 26 条
[1]   INSITU BEHAVIOR OF THE PYRIMIDINE PATHWAY ENZYMES IN SACCHAROMYCES-CEREVISIAE .3. CATALYTIC AND REGULATORY PROPERTIES OF CARBAMYL-PHOSPHATE SYNTHETASE - CHANNELING OF CARBAMYL-PHOSPHATE TO ASPARTATE-TRANSCARBAMYLASE [J].
BELKAID, M ;
PENVERNE, B ;
HERVE, G .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1988, 262 (01) :171-180
[2]  
BOETTCHER BR, 1980, J BIOL CHEM, V255, P7129
[3]   A PROTONATED HISTIDINE RESIDUE IN A PHOSPHORYLATION SITE FOR CYCLIC AMP-DEPENDENT PROTEIN-KINASE - COMPARISON OF A SYNTHETIC PEPTIDE WITH THE EXPOSED LINKING REGION IN THE MULTIENZYME POLYPEPTIDE CAD [J].
CARREY, EA .
BIOCHEMICAL JOURNAL, 1992, 287 :791-795
[4]   NUCLEOTIDE LIGANDS PROTECT THE INTER-DOMAIN REGIONS OF THE MULTIFUNCTIONAL POLYPEPTIDE CAD AGAINST LIMITED PROTEOLYSIS, AND ALSO STABILIZE THE THERMOLABILE PART-REACTIONS OF THE CARBAMOYL-PHOSPHATE SYNTHASE-II DOMAINS WITHIN THE CAD POLYPEPTIDE [J].
CARREY, EA .
BIOCHEMICAL JOURNAL, 1986, 236 (02) :327-335
[5]   PHOSPHORYLATION AND ACTIVATION OF HAMSTER CARBAMYL-PHOSPHATE SYNTHETASE-II BY CAMP-DEPENDENT PROTEIN-KINASE - A NOVEL MECHANISM FOR REGULATION OF PYRIMIDINE NUCLEOTIDE BIOSYNTHESIS [J].
CARREY, EA ;
CAMPBELL, DG ;
HARDIE, DG .
EMBO JOURNAL, 1985, 4 (13B) :3735-3742
[6]   MAPPING OF CATALYTIC DOMAINS AND PHOSPHORYLATION SITES IN THE MULTIFUNCTIONAL PYRIMIDINE-BIOSYNTHETIC PROTEIN CAD [J].
CARREY, EA ;
HARDIE, DG .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1988, 171 (03) :583-588
[7]   DOUBLE REGULATION BY UTP OF THE MAMMALIAN CARBAMOYL PHOSPHATE SYNTHASE-II ACTIVITY [J].
CARREY, EA .
BIOCHEMICAL SOCIETY TRANSACTIONS, 1989, 17 (04) :761-762
[8]  
CHRISTOPHERSON RI, 1980, J BIOL CHEM, V255, P1381
[9]  
COLEMAN PF, 1977, J BIOL CHEM, V252, P6379
[10]   KINETIC STUDIES OF BOVINE LIVER CARBAMOYL PHOSPHATE SYNTHETASE [J].
ELLIOTT, KRF ;
TIPTON, KF .
BIOCHEMICAL JOURNAL, 1974, 141 (03) :807-816
123