A STUDY OF THE BINDING OF VANCOMYCIN TO DIPEPTIDES USING CAPILLARY ELECTROPHORESIS

被引：62

作者：

CARPENTER, JL

CAMILLERI, P

DHANAK, D

GOODALL, D

机构：

[1] SMITHKLINE BEECHAM,THE FRYTHE,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND

[2] UNIV YORK,DEPT CHEM,YORK YO1 5DD,N YORKSHIRE,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 11期

关键词：

D O I：

10.1039/c39920000804

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Capillary electrophoresis (CE) has been used as a rapid technique for the determination of the absolute binding constants of dipeptides with vancomycin in solution; the values obtained for the mucopeptide mimic N-acetyl-D-Ala-D-Ala and related dipeptides are in good agreement with values reported in the literature using either differential UV spectrometry or NMR.

引用

页码：804 / 806

页数：3

共 12 条

[1] THE STRUCTURE AND MODE OF ACTION OF GLYCOPEPTIDE ANTIBIOTICS OF THE VANCOMYCIN GROUP [J].