ACTIVITY RHYTHMS IN INBRED MICE .1. GENETIC-ANALYSIS WITH RECOMBINANT INBRED STRAINS

被引：11

作者：

BEAU, J

机构：

[1] Genétique, Neurogénétique et Comportement, Université Paris V, CNRS URA 1294, Paris Cedex 6, 75270

来源：

BEHAVIOR GENETICS | 1991年 / 21卷 / 02期

关键词：

CHRONOBIOLOGY; GENETIC ANALYSIS; CIRCADIAN RHYTHM; CYCLE; MICE; ACTIVITY; RECOMBINANT INBRED; RECIPROCAL F1'S; C57BL/6BY; BALB/CBY;

D O I：

10.1007/BF01066331

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Rhythm of activity of inbred mice was recorded automatically by a set of actographs. This rhythm was characterized by six indices in the temporal and frequency domains. Two methods of genetic analysis were applied to these indices using parental strains BALB/c and C57BL/6, the reciprocal F1's, and the seven recombinant inbred strains (RI). Findings in the F1's show no maternal effect but indicate dominance and heterosis. The RI method successfully rejects the hypothesis of a monogenetic correlate for all measures. In line with F1 data, it demonstrates the presence of a polygenetic correlate: at least one other locus is involved in each of the six outcome parameters.

引用

页码：117 / 129

页数：13

共 21 条

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[2]

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[3]

BEAU J, 1988, J INTERDISCIPL CYCLE, V19, P129

[4]

BEAU J, 1986, GENETIC APPROACHES B, P19