INTRODUCTION OF A NOMENCLATURE - LEUKOTRIENES

被引：259

作者：

SAMUELSSON, B

BORGEAT, P

HAMMARSTROM, S

MURPHY, RC

机构：

[1] Dept. of Chemistry, Karolinska Institutet

来源：

PROSTAGLANDINS | 1979年 / 17卷 / 06期

基金：

美国国家卫生研究院; 英国医学研究理事会;

关键词：

D O I：

10.1016/0090-6980(79)90052-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The structure of a slow reacting substance (SRS) from mouse mastocytoma cells was recently reported (Murphy, R.C., Hammarström, S. and Samuelsson, B. (1979) Proc. Natl. Acad. Sci. USA, in press). We proposed that SRS is formed from a previously described unstable epoxide intermediate in the formation of dihydroxylated arachidonic acid metabolites in leukocytes. The term leukotriene is introduced for compounds which like SRS are non-cyclized C20 carboxylic acids with one or two oxygen substituents and three conjugated double bonds. © 1979.

引用

页码：785 / 787

页数：3