Dexamethasone in Preventing Post-Dural Puncture Headache : a randomized, double-blind, placebo-controlled trial

被引:0
作者
Doroudian, M. R. [1 ]
Norouzi, M. [1 ]
Esmailie, M. [1 ]
Tanhaeivash, R. [2 ]
机构
[1] Kerman Med Univ, Dept Anesthesiol, Kerman, Iran
[2] Farzan Clin Res Inst, Tehran, Iran
关键词
Dexamethasone; Post-Dural Puncture Headache; Spinal anesthesia;
D O I
暂无
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Spinal anesthesia is major complication is Post-Dural Puncture Headache (PDPH) which is an intense and debilitating event. We decided to assess if intravenous administration of dexamethasone can decrease the incidence and/or intensity of this kind of headache. For this purpose 178 patients, who were supposed to undergo lower extremity orthopedic surgery, were enrolled in the study . Before spinal anesthesia was initiated, the first group (DXM-group) received 2 ml, intravenous (IV) dexamethasone whereas the second group (PCB-group) received 2 mL IV normal saline. After termination of surgery, a 7 days follow-up started to observe the possible occurrence and intensity of PDPH. There was no statistically significant difference between DMX and PCB groups regarding the incidence of PDPH. IIowever, the intensity of headache differed between the two groups being less severe if IV dexamethasone had been given prophylactically. Dexamethasone can be used to decrease the severity of PDPH in patients who receive spinal anesthesia.
引用
收藏
页码:143 / 146
页数:4
相关论文
共 50 条
[21]   Dexamethasone and post-adenotonsillectomy pain in children Double-blind, randomized controlled trial [J].
Kang, Young ;
Ku, Eu Jeong ;
Jung, Il Gu ;
Kang, Min Hyuck ;
Choi, Young-Seok ;
Jung, Hahn Jin .
MEDICINE, 2021, 100 (02) :E24122
[22]   The Prophylactic Effect of Acetaminophen and Caffeine on Post Dural Puncture Headache after Spinal Anesthesia for Cesarean Section: A Randomized Double-Blind Clinical Trial [J].
Hadavi, Seyed Mohammad Reza ;
Panah, Ashkan ;
Shamohammadi, Sona ;
Nejad, Fatemeh Kanaani ;
Sahmeddini, Mohammad Ali ;
Asmarian, Naeimehossadat .
IRANIAN JOURNAL OF MEDICAL SCIENCES, 2024, 49 (09) :573-579
[23]   Response to question: Is intranasal oxytocin useful in preventing post-dural puncture headache in caesarean section? A randomised clinical trial [J].
Mashak, Banafsheh ;
Pouryaghobi, Seyyed Mohsen ;
Ataei, Mina ;
Bagheri, Ramesh Baradaran ;
Gelsefid, Saeid Hasani ;
Rastad, Hadith ;
Farahani, Masoumeh ;
Balaneji, Souzan Soufizadeh .
FAMILY MEDICINE AND PRIMARY CARE REVIEW, 2024, 26 (01) :62-66
[24]   Efficacy of pharmacological therapies for preventing post-dural puncture headaches in obstetric patients: a Bayesian network meta-analysis of randomized controlled trials [J].
Zhao, Ge ;
Song, Guang ;
Liu, Jing .
BMC PREGNANCY AND CHILDBIRTH, 2023, 23 (01)
[25]   Gabapentin in the Management of Pain following Tonsillectomy: A Randomized Double-Blind Placebo-Controlled Trial [J].
Sanders, James G. ;
Cameron, Claire ;
Dawes, Patrick J. D. .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2017, 157 (05) :781-790
[26]   Effectiveness of Lateral Decubitus Position for Preventing Post-Dural Puncture Headache: A Meta-Analysis [J].
Zorrilla-Vaca, Andres ;
Makkar, Jeetinder Kaur .
PAIN PHYSICIAN, 2017, 20 (04) :E521-E529
[27]   Dexamethasone and post-dural puncture headache in women who underwent cesarean delivery under spinal anesthesia: A systemic review and meta-analysis of randomized controlled trials [J].
Fenta, Efrem ;
Kibret, Simegnew ;
Hunie, Metages ;
Teshome, Diriba .
ANNALS OF MEDICINE AND SURGERY, 2021, 62 :104-113
[28]   How does dexamethasone influence surgical outcome after laparoscopic Nissen fundoplication? A randomized double-blind placebo-controlled trial [J].
Schietroma M. ;
Giuliani M. ;
Zoccali G. ;
Carnei F. ;
Bianchi Z. ;
Gleni Z. ;
Amicucci G. .
Updates in Surgery, 2010, 62 (1) :47-54
[29]   Dexamethasone to prevent postextubation airway obstruction in adults: a prospective, randomized, double-blind, placebo-controlled study [J].
Chao-Hsien Lee ;
Ming-Jen Peng ;
Chien-Liang Wu .
Critical Care, 11
[30]   Sphenopalatine ganglion block with or without greater occipital nerve block for treatment of obstetric post-dural puncture headache after spinal anesthesia: randomized controlled trial [J].
Elshafei, Amr Shaaban ;
Mowafy, Sherif M. S. .
AIN SHAMS JOURNAL OF ANESTHESIOLOGY, 2023, 15 (01)