Combination Antibiotic Therapy in Pan-Resistant Klebsiella pneumoniae Infection: A Report of Two Cases

被引：3

作者：

Emre, Salih ^{[1
]}

Moroglu, Cigdem ^{[1
]}

Yildirmak, Taner ^{[1
]}

Simsek, Funda ^{[1
]}

Arabaci, Cigdenn ^{[1
]}

Ozkaya, Ozay ^{[2
]}

Turgut, Namigar ^{[3
]}

Irmak, Merve ^{[4
]}

机构：

[1] Okmeydani Egitim & Arastirma Hastanesi, Infeksiyon Hastaliklari & Klin Mikrobiyol Klin, Istanbul, Turkey

[2] Okmeydani Egitim & Arastirma Hastanesi, Plast Rekonstruktif & Estet Cerrahi Klin, Istanbul, Turkey

[3] Okmeydani Egitim & Arastirma Hastanesi, Anesteziyol & Reanimasyon Klin, Istanbul, Turkey

[4] Okmeydani Egitim & Arastirma Hastanesi, Hastaliklari Klin, Istanbul, Turkey

来源：

KLIMIK JOURNAL | 2018年 / 31卷 / 02期

关键词：

Multiple drug resistance; carbapenems; Klebsiella pneumoniae; colistin;

D O I：

10.5152/kd.2018.40

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Infections caused by resistant Gram-negative bacteria are seen in increasing frequency. Colistin is used in the treatment of these infections but colistin-resistant bacteria and pan-resistant bacteria have emerged. This situation is thought to become an important health problem in the near future. Various combination therapies are used in the infections caused by pan-resistant bacteria. Double-carbapenem regimen, with or without colistin, is used for this purpose. In this report, we present two different cases of pan-resistant Klebsiella pneumoniae infection, first one developing on a necrotic skin lesion, and second one occurring as central venous catheter-related bacteremia during the treatment of a urinary tract infection, treated with double carbapenems, one of them together with colistin.

引用

页码：169 / 172

页数：4

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