A ROLE FOR CD8+ LYMPHOCYTES-T IN THE PATHOGENESIS OF AIDS

被引：11
作者：
ARANDAANZALDO, A
机构：
[1] Laboratoire d'Immunobiologie, Faculté de Médecine Paris V, 75270 Paris Cedex 06
来源：
RESEARCH IN IMMUNOLOGY | 1991年 / 142卷 / 07期
关键词：
AIDS; HIV; REPLICATION; LYMPHOCYTE-T; IMMUNOSUPPRESSION; CLONAL ANERGY; GRAFT VS; HOST DISEASE; EXPERIMENTAL IMMUNODEFICIENCY; POSITION PAPER;
D O I：
10.1016/0923-2494(91)90099-5
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Experimental and clinical evidence is presented which supports the hypothesis that CD8+ T lymphocytes aimed at suppressing HIV replication in infected CD4+ T cells may have an important role in the pathogenesis of AIDS by directly causing a decrease in CD4+ T lymphocyte numbers. Possible models to test this hypothesis are discussed.
引用
收藏
页码：541 / 550
页数：10
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