DILEMMA REGARDING AN ACTIVE-SITE MODEL FOR PORCINE PANCREATIC LIPASE

被引：61

作者：

HULTIN, PG ^{[1
]}

JONES, JB ^{[1
]}

机构：

[1] UNIV TORONTO,DEPT CHEM,80 ST GEORGE ST,TORONTO M5S 1A1,ONTARIO,CANADA

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 11期

基金：

加拿大自然科学与工程研究理事会;

关键词：

PORCINE PANCREATIC LIPASE; ACTIVE SITE MODEL; STEREOSELECTIVITY; CHIRAL SYNTHON; ESTER HYDROLYSIS;

D O I：

10.1016/S0040-4039(00)91631-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An active-site model for porcine pancreatic lipase (PPL) is described that focuses further attention on the factors determining PPL-specificity in order to facilitate the development of a comprehensive active site model that will be universally applicable in all asymmetric synthetic applications of the enzyme.

引用

页码：1399 / 1402

页数：4

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