2 UNUSUAL NEUROLOGICAL PRESENTATIONS OF GRANULOCYTIC SARCOMA IN PHILADELPHIA-POSITIVE CHRONIC MYELOID-LEUKEMIA

被引:13
作者
MAHENDRA, P
AGER, S
BEDLOW, AJ
BLOXHAM, DM
GREEN, AR
MARCUS, RE
机构
[1] Department of Haematology, Addenbrookes NHS Trust, Cambridge
关键词
GRANULOCYTIC SARCOMA; CHRONIC MYELOID LEUKEMIA; NEUROLOGICAL PRESENTATION;
D O I
10.3109/10428199409049735
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Granulocytic sarcoma (GS) is a rare extramedullary tumour consisting of immature myeloid precursors. It occurs most commonly in association with myeloid leukaemias and myeloproliferative disorders. Rarely there may be no evidence of haematological malignancy. We describe neurological presentations of GS in two patients with Philadelphia (Ph) positive chronic myeloid leukaemia (CML). In both cases the bone marrow was in chronic phase at the time of presentation of the GS, but there was rapid subsequent transformation into the blastic phase.
引用
收藏
页码:351 / 355
页数:5
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