2-Trifluoromethyl-10H-benzo[4,5]imidazo[1,2-a] pyrimidin-4-one

被引:1
作者
Chandra [1 ]
Puttaraju, K. B. [2 ]
Shivashankar, K. [2 ]
Babu, E. A. Jithesh [1 ]
Mahendra, M. [1 ]
机构
[1] Univ Mysore, Dept Studies Phys, Mysore 570006, Karnataka, India
[2] Bangalore Univ, Dept Chem, Bangalore 560001, Karnataka, India
关键词
D O I
10.1107/S160053681302401X
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
In the molecule of the title compound, C11H6F3N3O, the three fused rings of the benzo[4,5] imidazo[1,2-a] pyrimidine unit are essentially coplanar, the maximum deviation from the mean plane being 0.096 (2) angstrom. In the crystal, N-H center dot center dot center dot O hydrogen bonds link the molecules into chains running along the b-axis direction.
引用
收藏
页码:O1536 / +
页数:8
相关论文
共 9 条
[1]   Benzimidazole condensed ring systems: New synthesis and antineoplastic activity of substituted 3,4-dihydro- and 1,2,3,4-tetrahydro-benzo[4,5]imidazo[1,2-a]pyrimidine derivatives [J].
Abdel-hafez, Atef Abdel-monem .
ARCHIVES OF PHARMACAL RESEARCH, 2007, 30 (06) :678-684
[2]   TABLES OF BOND LENGTHS DETERMINED BY X-RAY AND NEUTRON-DIFFRACTION .1. BOND LENGTHS IN ORGANIC-COMPOUNDS [J].
ALLEN, FH ;
KENNARD, O ;
WATSON, DG ;
BRAMMER, L ;
ORPEN, AG ;
TAYLOR, R .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 1987, (12) :S1-S19
[3]  
Bruker, 2012, APEX2 SAINT
[4]   Structure-activity relationship study of novel tissue transglutaminase inhibitors [J].
Duval, E ;
Case, A ;
Stein, RL ;
Cuny, GD .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (07) :1885-1889
[5]  
Nunes J. J., 2005, Chem. Abstr, V142, P298123, Patent No. [2005009443, WO2005009443]
[6]   The aza-Wittig reaction: an efficient tool for the construction of carbon-nitrogen double bonds [J].
Palacios, Francisco ;
Alonso, Concepcion ;
Aparicio, Dornitila ;
Rubiales, Gloria ;
de los Santos, Jesus M. .
TETRAHEDRON, 2007, 63 (03) :523-575
[7]   A short history of SHELX [J].
Sheldrick, George M. .
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2008, 64 :112-122
[8]   Structure validation in chemical crystallography [J].
Spek, Anthony L. .
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 2009, 65 :148-155
[9]   Shaken not stirred:: A facile synthesis of 1,4-bis(furo[2,3-d]pyrimidine-2,4(1H,3H)-dione-5-yl)benzenes by one-pot reaction of isocyanides, N,N′-dimethylbarbituric acid, and terephthaldialdehyde [J].
Teimouri, Mohammad Bagher ;
Bazhrang, Reihaneh .
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (14) :3697-3701