NOVEL NON-SQUALENOID PHOTOAFFINITY LABELS FOR MAMMALIAN SQUALENE EPOXIDASE

被引：8

作者：

CERUSO, M ^{[1
]}

PRESTWICH, GD ^{[1
]}

机构：

[1] SUNY STONY BROOK,DEPT CHEM,STONY BROOK,NY 11794

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 18期

关键词：

D O I：

10.1016/S0960-894X(00)80067-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Specific affinity labeling of the squalene binding site of squalene epoxidase remains an elusive goal. We wish to report here the design and synthesis of six novel, non-squalenoid, photoaffinity labels for squalene epoxidase, based on the potent inhibitor NB-598 (3).

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页码：2179 / 2184

页数：6

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