PAPILLOMAVIRUS INFECTION AND CERVICAL CANCER INCIDENCE IN PRE-VACCINATION AND THE INITIAL VACCINATION PERIODS IN THE REPUBLIC OF SAKHA (YAKUTIA)

The research aims at studying patterns and regional characteristics of morbidity and incidence of various papillomavirus infection and cervical cancer forms in the Republic of Sakha (Yakutia) in the pre-vaccination period and the first years of vaccination against this pathology. It is established that the studied periods do not show any significant differences or decreasing trend in anogenital (venereal) warts morbidity. The study revealed higher (by 1/6-2 times) incidence of high-risk HPV of type 16 in women, compared with men. There was no decrease in type 16 and 18 HPV incidence in 2008-2011 (the period of introducing low vaccination coverage), compared with the year 2007. There is a trend for increased CC morbidity in women aged 30-44 years.