INCORPORATION OF LACTATE MEASUREMENT IN MULTI-SPIN-ECHO PROTON SPECTROSCOPIC IMAGING

被引：30
作者：
DUYN, JH
FRANK, JA
MOONEN, CTW
机构：
[1] NIH,NATL CTR RES RESOURCES,IN VIVO NMR RES CTR,BIOMED ENGN & INSTRUMENTAT PROGRAM,BETHESDA,MD 20892
[2] NIH,OFF INTRAMURAL RES,DIAGNOST RADIOL RES LAB,BETHESDA,MD 20892
来源：
MAGNETIC RESONANCE IN MEDICINE | 1995年 / 33卷 / 01期
关键词：
MR PROTON SPECTROSCOPY; MR PROTON SPECTROSCOPIC IMAGING; LACTATE EDITING; LIPID SUPPRESSION;
D O I：
10.1002/mrm.1910330115
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
An improved multi-slice, multi-spin-echo proton spectroscopic imaging method for human brain is presented. The technique allows the reconstruction of lactate images, along with choline plus creatine, N-acetylaspartate, and lipid images from one single data set processed in three separate ways. The discrimination between resonances of lipid protons and lactate methyl protons is based on homonuclear spin-spin coupling. The reliability of the separation of the lipid and lactate contribution depends on the T-2 of the lipid resonances. Measurements were performed on a standard 1.5 Tesla clinical scanner on healthy Volunteers and a patient with high grade CNS lymphoma, demonstrating the ability to obtain high quality metabolite maps within 11 min.
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页码：101 / 107
页数：7
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