A NOVEL AND EFFICIENT SYNTHESIS OF A TETRA-SUBSTITUTED IMIDAZOLE

被引：10
|
作者：
HAYES, JF [1 ]
MITCHELL, MB [1 ]
PROCTOR, G [1 ]
机构：
[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND
来源：
TETRAHEDRON LETTERS | 1994年 / 35卷 / 02期
关键词：
D O I：
10.1016/S0040-4039(00)76529-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel synthesis of a tetra-substituted imidazole is described. A key feature of the synthesis is the regioselective deprotonation of picolylpyrrolidinone 3 and the efficient reaction of this anion with an aryl nitrile to give the pyrrolidinoimidazole nucleus in a single step.
引用
收藏
页码：273 / 274
页数：2
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