A NOVEL AND EFFICIENT SYNTHESIS OF A TETRA-SUBSTITUTED IMIDAZOLE

被引：10

作者：

HAYES, JF ^{[1
]}

MITCHELL, MB ^{[1
]}

PROCTOR, G ^{[1
]}

机构：

[1] UNIV SALFORD,DEPT CHEM & APPL CHEM,SALFORD M5 4WT,LANCS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 02期

关键词：

D O I：

10.1016/S0040-4039(00)76529-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel synthesis of a tetra-substituted imidazole is described. A key feature of the synthesis is the regioselective deprotonation of picolylpyrrolidinone 3 and the efficient reaction of this anion with an aryl nitrile to give the pyrrolidinoimidazole nucleus in a single step.

引用

页码：273 / 274

页数：2

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