Chemistry and Biology of Secondary Metabolites from Aspergillus Genus

被引：35
作者：
Zhang, Xiaolei [1 ]
Li, Zhi [1 ]
Gao, Jiangtao [1 ]
机构：
[1] Fujian Agr & Forestry Univ, Coll Life Sci, Fuzhou 350002, Fujian, Peoples R China
来源：
NATURAL PRODUCTS JOURNAL | 2018年 / 8卷 / 04期
关键词：
Aspergillus; secondary metabolites; structure; biological activity; ubiquitous fungi; genome sequencing;
D O I：
10.2174/2210315508666180501154759
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the genus produces a wide range of structurally diverse secondary metabolites that are of highly considerable interest to both scientific research community and pharmaceutical industry. Genome sequencing results have indicated that chemical diversity of secondary metabolites is much larger in each species than previously thought. This review summarizes a total of 315 new secondary metabolites of Aspergillus reported from 2015 to 2017 and demonstrates the therapeutical potential of this genus by introducing their unique chemical structures and excellent bioactivities from this genus.
引用
收藏
页码：275 / 304
页数：30
相关论文
共 50 条
  • [41] PHYLOGENETIC ANALYSIS IN GENUS EUCHRESTA BASED ON SECONDARY METABOLITES
    MATSUURA, N
    IINUMA, M
    TANAKA, T
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 1994, 22 (06) : 621 - 629
  • [42] Secondary metabolites in in vitro cultured plants of the genus Drosera
    Marczak, L
    Kawiak, A
    Lojkowska, E
    Stobiecki, M
    PHYTOCHEMICAL ANALYSIS, 2005, 16 (03) : 143 - 149
  • [43] Secondary metabolites of Aspergillus exert immunobiological effects on human monocytes
    Rossano, F
    De Luna, LO
    Buommino, E
    Cusumano, V
    Losi, E
    Catania, MR
    RESEARCH IN MICROBIOLOGY, 1999, 150 (01) : 13 - 19
  • [44] Recent advances in genome mining of secondary metabolites in Aspergillus terreus
    Guo, Chun-Jun
    Wang, Clay C. C.
    FRONTIERS IN MICROBIOLOGY, 2014, 5
  • [45] Exploring the potential of Aspergillus wentii: secondary metabolites and biological properties
    Ainousah, Bayan E.
    Ibrahim, Sabrin R. M.
    Alzain, Abdulrahim A.
    Mohamed, Shaimaa G. A.
    Hussein, Hazem G. A.
    Ashour, Ahmed
    Abdallah, Hossam M.
    Mohamed, Gamal A.
    ARCHIVES OF MICROBIOLOGY, 2024, 206 (05)
  • [46] Chemistry and biology of genus Wedelia Jacq.: A review
    Verma, Nitin
    Khosa, R. L.
    INDIAN JOURNAL OF NATURAL PRODUCTS AND RESOURCES, 2015, 6 (02): : 71 - 90
  • [47] Secondary Metabolites of Marine Microbes: From Natural Products Chemistry to Chemical Ecology
    Petersen, Lars-Erik
    Kellermann, Matthias Y.
    Schupp, Peter J.
    YOUMARES 9 - THE OCEANS: OUR RESEARCH, OUR FUTURE, 2020, : 159 - 180
  • [48] Secondary metabolites from cyanobacteria: source, chemistry, bioactivities, biosynthesis and total synthesis
    He, Yanchun
    Chen, Ying
    Tao, Huaming
    Zhou, Xuefeng
    Liu, Juan
    Liu, Yonghong
    Yang, Bin
    PHYTOCHEMISTRY REVIEWS, 2024, 24 (1) : 483 - 525
  • [49] Secondary Metabolites from the South China Sea Invertebrates: Chemistry and Biological Activity
    Zhang, Wen
    Guo, Yue-Wei
    Gu, Yucheng
    CURRENT MEDICINAL CHEMISTRY, 2006, 13 (17) : 2041 - 2090
  • [50] Chemical Diversity and Biological Properties of Secondary Metabolites from Sea Hares of Aplysia Genus
    Pereira, Renato B.
    Andrade, Paula B.
    Valentao, Patricia
    MARINE DRUGS, 2016, 14 (02):
12345