Chemistry and Biology of Secondary Metabolites from Aspergillus Genus

被引：35
作者：
Zhang, Xiaolei [1 ]
Li, Zhi [1 ]
Gao, Jiangtao [1 ]
机构：
[1] Fujian Agr & Forestry Univ, Coll Life Sci, Fuzhou 350002, Fujian, Peoples R China
来源：
NATURAL PRODUCTS JOURNAL | 2018年 / 8卷 / 04期
关键词：
Aspergillus; secondary metabolites; structure; biological activity; ubiquitous fungi; genome sequencing;
D O I：
10.2174/2210315508666180501154759
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Aspergillus is a genus of ubiquitous fungi that are therapeutically important because the genus produces a wide range of structurally diverse secondary metabolites that are of highly considerable interest to both scientific research community and pharmaceutical industry. Genome sequencing results have indicated that chemical diversity of secondary metabolites is much larger in each species than previously thought. This review summarizes a total of 315 new secondary metabolites of Aspergillus reported from 2015 to 2017 and demonstrates the therapeutical potential of this genus by introducing their unique chemical structures and excellent bioactivities from this genus.
引用
收藏
页码：275 / 304
页数：30
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