SIGNAL TRANSDUCTION THROUGH THE T-CELL ANTIGEN RECEPTOR

被引：45

作者：

ABRAHAM, RT

KARNITZ, LM

SECRIST, JP

LEIBSON, PJ

机构：

[1] Department of Immunology, Mayo Clinic, Rochester

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1992年 / 17卷 / 10期

关键词：

D O I：

10.1016/0968-0004(92)90015-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The mechanism by which ligand binding to the T-cell antigen receptor triggers the T-cell activation program has long been one of the most fascinating questions in lymphocyte biology. Here, we review recent insights into the transmembrane signaling functions of this multisubunit receptor complex.

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页码：434 / 438

页数：5

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